SPEAKER: The factor date after 70 is because, when they decided the trial and they decided the approach, they were in unknown area. That was the area where lower than 40, you didn't really know what would have happened. And we have to appreciate that. Nowadays, we know we can go as low as 10, but we didn't know at the time that things were designed. So the 70 was there in a way, also in the trial design of the Odyssey, just because there was uncertainty in that area.

But now, there is no reason anymore. I mean, it's a choice. If a physician feels to use the 75, it's fine. But we have sort of a biased view, in the sense that we are lipidologists, so we know that if we go low with the LDL, it's not the problem, but there is only a benefit. So we trust in data and we go.